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Semaglutide reconstitution chart
How many units to draw for Semaglutide on a U-100 insulin syringe, for every common vial size and water amount.
These charts are arithmetic for a U-100 insulin syringe (1 unit = 0.01 mL), not dose recommendations. Use the dose from your own protocol, and double-check every draw.
Quick answer
A Semaglutide 10 mg vial mixed with 2 mL of bacteriostatic water is 5 mg per mL. Every unit on a U-100 syringe is 0.01 mL, so 10 units = 0.5 mg (500 mcg) and 1 mg = 20 units. Change the water and every number changes, which is why "how many units" only makes sense next to the vial size and the water.
Semaglutide units charts
Semaglutide 5 mg vial
| Water added | Strength | 5 units = | 10 units = | 25 units = | 1 mg = | Whole vial | Calculator |
|---|---|---|---|---|---|---|---|
| 1 mL | 5 mg/mL | 0.25 mg (250 mcg) | 0.5 mg (500 mcg) | 1.25 mg | 20 units | 100 units | Open |
| 2 mL | 2.5 mg/mL | 0.125 mg (125 mcg) | 0.25 mg (250 mcg) | 0.625 mg (625 mcg) | 40 units | 200 units | Open |
| 3 mL | 1.67 mg/mL | 0.083 mg (83 mcg) | 0.167 mg (167 mcg) | 0.417 mg (417 mcg) | 60 units | 300 units | Open |
Semaglutide 10 mg vial
| Water added | Strength | 5 units = | 10 units = | 25 units = | 1 mg = | Whole vial | Calculator |
|---|---|---|---|---|---|---|---|
| 1 mL | 10 mg/mL | 0.5 mg (500 mcg) | 1 mg | 2.5 mg | 10 units | 100 units | Open |
| 2 mL | 5 mg/mL | 0.25 mg (250 mcg) | 0.5 mg (500 mcg) | 1.25 mg | 20 units | 200 units | Open |
| 3 mL | 3.33 mg/mL | 0.167 mg (167 mcg) | 0.333 mg (333 mcg) | 0.833 mg (833 mcg) | 30 units | 300 units | Open |
Semaglutide 20 mg vial
| Water added | Strength | 5 units = | 10 units = | 25 units = | 1 mg = | Whole vial | Calculator |
|---|---|---|---|---|---|---|---|
| 1 mL | 20 mg/mL | 1 mg | 2 mg | 5 mg | 5 units | 100 units | Open |
| 2 mL | 10 mg/mL | 0.5 mg (500 mcg) | 1 mg | 2.5 mg | 10 units | 200 units | Open |
| 3 mL | 6.67 mg/mL | 0.333 mg (333 mcg) | 0.667 mg (667 mcg) | 1.67 mg | 15 units | 300 units | Open |
Different numbers? The reconstitution calculator works for any vial, water and dose, and shows the mark on a syringe. New to mixing? See the step-by-step guide with pictures.
How to read the chart
mg in a draw = units ÷ 100 × strength
units for a dose = dose (mg) ÷ strength × 100
More water makes each unit weaker, so the same dose takes more units and is easier to measure. The water never changes how much Sema is in the vial, only how many units each dose is.
Track your Sema vials
Enter your vial and water once and PepKeep does this math at every dose: the reminder shows the exact units to draw, each logged dose comes out of the vial, and you see how many doses are left, the day it runs out, and what each shot costs. It works for step-up plans and on/off cycles too, on iPhone, Android and desktop. Try it free for 7 days, no card needed.
Questions
How many units is 1 mg of Semaglutide in a 10 mg vial with 2 mL of water?
20 units on a U-100 syringe. 10 mg ÷ 2 mL = 5 mg per mL, and 1 mg ÷ 5 mg per mL = 0.2 mL, which is 20 units.
How much bacteriostatic water should I add to Semaglutide?
Any amount that makes your dose easy to read on your syringe. More water means more units per dose; it never changes how many mg are in the vial. Pick a water amount, then use the chart or calculator to see where your dose lands.
Does the syringe size change the units?
No. On every U-100 insulin syringe, 1 unit is 0.01 mL. A 0.3 mL or 0.5 mL syringe just holds fewer units; each unit is the same size.
Is this a dosing guide?
No. It converts mg, mL and units. It doesn't recommend a dose; use the one from your own protocol and clinician.
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Sources
Peptide facts come from these sources. The chart itself is arithmetic.